Proin (phenylpropanolamine) is a medication your veterinarian can prescribe to help your dog with urinary incontinence. Signs of urinary incontinence in dogs include dripping or leaking urine, needing to go to the bathroom more often than usual, red, irritated skin around the genital region, wetting the sleeping area, excessively licking the genital region, and urinating inappropriately in the house.
The active ingredient in the medication is phenylpropanolamine. Phenylpropanolamine is an adrenergic agent that tightens the dog's urinary sphincter, which helps manage urinary incontinence. Phenylpropanolamine will reduce or eliminate accidents in the house, improve your dog's urinary control, and minimize skin irritation and redness around your dog's genital area.
Tell your veterinarian if your dog is allergic to phenylpropanolamine. Your vet needs to know if your dog is pregnant or nursing. You should discuss all of your dog's medical problems with your veterinarian, especially heart problems, glaucoma, diabetes, hypothyroidism, and high blood pressure.
You should also discuss all of the medications and dietary supplements your dog takes, both prescription and over-the-counter. Some drugs affect the way phenylpropanolamine works, including non-steroid anti-inflammatory drugs (NSAIDs), such as Rimadyl or aspirin, beta blocks, such as atenolol, and tricyclic antidepressants, such as clomipramine.
Stop giving phenylpropanolamine to your dog and seek immediate medical attention if your dog exhibits signs of an allergic reaction, such as hives, breathing difficulties, and swelling of the tongue, lips, or face.
Other side effects may also occur, including restlessness, loss of appetite, increased blood pressure, increased heart rate, and irritability. Increased thirst, vomiting, diarrhea, weakness, vocalization, excessive panting, confusion, and excessive salivation may also occur. Talk to your veterinarian about any side effects you observe.
Do not give your dog epinepherine or ephedrine while he's taking phenylpropanolamine. You should not give your dog phenylpropanolamine within two weeks of taking an MAOI, such selegiline or Preventic Collar.
Phenylpropanolamine comes in 25mg, 50mg, and 75mg chewable, liver-flavored tablets. The usual dose of phenylpropanolamine is 0.4-0.8mg per pound. The medication is typically given twice a day, every 12 hours. Follow your veterinarian's instructions on how much and when to give the medication to your dog.
Phenylpropanolamine should be kept at room temperature between 68 and 77-degrees Fahrenheit. Keep the medication away from moisture and out of reach from children and pets.